YARA (created by Victor Alvarez at VirusTotal) is a rule-based pattern-matching tool used to identify and classify files especially malware by detecting specific textual, binary, or structural signatures.
CAPA (by Mandiant) identifies malware capabilities by analyzing executable behavior and mapping it to known techniques.
SIGMA is a generic, open signature format that allows security analysts to write detection rules that can be applied across different SIEM systems.